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Idiopathic intestinal pseudo-obstruction and contaminated small bowel syndrome--treatment with metronidazole, ileostomy, and indomethacin.

Abstract
A 28-year-old Iranian man with chronic idiopathic intestinal pseudo-obstruction presented with gross features of contaminated bowel syndrome. Treatment with metronidazole reversed steatorrhea but exacerbated the gaseous distention of the small intestine, precipitating emergency surgical decompression and ileostomy. A chronic high volume ileostomy diarrhea ensued and was successfully treated with oral indomethacin.
AuthorsA Keshavarzian, P Isaacs, I McColl, G E Sladen
JournalThe American journal of gastroenterology (Am J Gastroenterol) Vol. 78 Issue 9 Pg. 562-5 (Sep 1983) ISSN: 0002-9270 [Print] United States
PMID6688501 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Metronidazole
  • Indomethacin
Topics
  • Adult
  • Body Weight
  • Constipation (etiology)
  • Humans
  • Ileostomy
  • Indomethacin (therapeutic use)
  • Intestinal Obstruction (surgery)
  • Intestinal Pseudo-Obstruction (complications, drug therapy, surgery)
  • Intestine, Small (microbiology)
  • Male
  • Metronidazole (therapeutic use)

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