Radiation nephritis in a case of a spindle cell neoplasm in remission after combination treatment with abdominal radiotherapy and chemotherapy.

Abstract

A 34-year-old woman presented with acute radiation nephritis three months after completion of treatment with cytotoxic chemotherapy and abdominal radiotherapy. This case and similar previous reports suggest a potentiating effect by the chemotherapy of the renal damage by radiation which may cause radiation nephritis to develop at radiation doses normally within renal tolerance.

• Authors: J A Ironside, P G Davey, J S Scott
• Journal: Clinical oncology (Clin Oncol) Vol. 9 Issue 2 Pg. 153-8 (Jun 1983) ISSN: 0305-7399 [Print] England
• PMID: 6688388 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vincristine
• Doxorubicin
• Cyclophosphamide
• Prednisone

Topics

• Abdominal Neoplasms (therapy)
• Adult
• Antineoplastic Combined Chemotherapy Protocols
• Cyclophosphamide (adverse effects)
• Doxorubicin (adverse effects)
• Female
• Humans
• Nephritis (etiology)
• Prednisone (adverse effects)
• Radiotherapy (adverse effects)
• Sarcoma (therapy)
• Vincristine (adverse effects)