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The effects of RO-22-4679, a thromboxane synthetase inhibitor, on ventricular fibrillation induced by coronary artery occlusion in conscious dogs.

AuthorsC B Huddleston, F M Lupinetti, K H Laws, J C Collins, J A Clanton, J J Hawiger, J A Oates, J W Hammon Jr
JournalCirculation research (Circ Res) Vol. 52 Issue 5 Pg. 608-13 (May 1983) ISSN: 0009-7330 [Print] United States
PMID6682723 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Enzyme Inhibitors
  • Imidazoles
  • Ro 22-4679
  • Oxidoreductases
  • Thromboxane-A Synthase
Topics
  • Animals
  • Blood Platelets (physiology)
  • Coronary Disease (complications)
  • Dogs
  • Enzyme Inhibitors (therapeutic use)
  • Imidazoles (pharmacology)
  • Myocardial Infarction (etiology)
  • Oxidoreductases (antagonists & inhibitors)
  • Platelet Aggregation
  • Regional Blood Flow
  • Thromboxane-A Synthase (antagonists & inhibitors)
  • Ventricular Fibrillation (etiology, prevention & control)

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