[Poisoning by diazomethane inhalation].

Abstract

A case of Diazomethane intoxication has been reported. Diazomethane is gaz commonly used by pharmacological and industrial chemist. This case of intoxication is rare, since only 15 other cases have been published up to now. A review of the literature leads leads describe the clinical feature of such an intoxication by gaz inhalation. When Diazomethane is inhaled it induces respiratory and general disorders. In some cases, it be fatal, and, in some other cases, when a second exposure happens, bronchial asthma may appear. Post mortem studies show pulmonary oedema lesions with important inflammatory reaction localized in the peribronchia. It must be emphasized that direct aggression is probably responsive of toxical discorders, but increase of the symptoms consecutive to a second exposure are related to allergical mechanisms.

• Authors: J P Stain, G Nouvet, P Morere
• Journal: Toxicological European research. Recherche europeenne en toxicologie (Toxicol Eur Res) Vol. 5 Issue 5 Pg. 217-9 (Sep 1983) ISSN: 0249-6402 [Print] France
• Vernacular Title: Intoxication par inhalation de diazométhane.
• PMID: 6675207 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Diazomethane

Topics

• Adult
• Asthma (chemically induced)
• Diazomethane (poisoning)
• Female
• Gas Poisoning (pathology, physiopathology)
• Humans
• Occupational Diseases (chemically induced, physiopathology)