Hemoglobin Setif and in vitro pseudosickling noted in a family with co-existent alpha and beta thalassemia.

Abstract	A Turkish Cypriot family was investigated for suspected heterozygous sickle cell disease, which had been reported in a maternal branch of the family resident in England. Two maternal grandparents were of African Negro origin. Pseudosickling was noted in members of the family who were found to have an abnormal hemoglobin fraction. This abnormal fraction proved to be Hemoglobin Setif (alpha 94 Asp leads to Tyr). Family studies demonstrated the presence of this hemoglobin in varying proportions in the mother and 2 of the 4 children. alpha and beta thalassemia traits are also present in several family members.
Authors	E Raik, E Powell, P Fleming, S Gordon
Journal	Pathology (Pathology) Vol. 15 Issue 4 Pg. 453-6 (Oct 1983) ISSN: 0031-3025 [Print] England
PMID	6674875 (Publication Type: Journal Article)
Chemical References	Hemoglobins, Abnormal Hemoglobin Setif
Topics	Adolescent Adult Anemia, Sickle Cell (genetics) Black People Electrophoresis, Cellulose Acetate Female Hemoglobins, Abnormal (genetics) Heterozygote Humans Male Middle Aged Pedigree Sickle Cell Trait (genetics) Thalassemia (genetics)

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