[Treatment of Wegener's granulomatosis using plasmapheresis].

Abstract

A case with Wegener's granulomatosis in a young woman is described. The diagnosis was made after extirpation and histological investigation of granuloma tissue from the nasal concha and by needle renal biopsy. A successful treatment was carried out with plasmapheresis, hemodialysis and immune-suppressors, the acute paroxysm being coped as well as the developed acute renal insufficiency. After each plasmapheresis a considerable reduction of the circulating immune complexes was established. After a remission of 9 months the patient developed a stage of terminal chronic renal insufficiency and was subjected to chronic dialysis with good rehabilitation.

• Authors: D Nenov, I Stanchev, M Gurdevski, D Paskalev, K Nenov
• Journal: Vutreshni bolesti (Vutr Boles) Vol. 22 Issue 6 Pg. 58-61 ( 1983) ISSN: 0506-2772 [Print] Bulgaria
• Vernacular Title: Lechenie na granulomatozata na Vegener s plazmafereza.
• PMID: 6673347 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Cyclophosphamide

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Adult
• Combined Modality Therapy
• Cyclophosphamide (therapeutic use)
• Female
• Granulomatosis with Polyangiitis (pathology, therapy)
• Humans
• Kidney (pathology)
• Plasmapheresis
• Renal Dialysis