[Erythrocyte filterability and treatment with pentoxifylline].

Abstract

The purpose of our study was to verify the possibility of obtaining a reduction in the erythrocyte filtration rate and an improvement in the O2 tissue uptake in twenty patients suffering from insulin-dependent diabetes mellitus and diabetic angiopathy, randomly divided in two groups receiving pentoxifylline (1,200 mg/day for 30 days) or a placebo solution, respectively. The erythrocyte filtration rate decreased in patients treated with pentoxifylline and the difference of erythrocyte filtration rate between the two groups was statistically significant.

• Authors: M Valentini, F Sciannameo, M Francucci, M Tockner, L Sassano, A Allegra
• Journal: La Ricerca in clinica e in laboratorio (Ric Clin Lab) Vol. 13 Suppl 3 Pg. 455-8 ( 1983) ISSN: 0390-5748 [Print] Italy
• Vernacular Title: Filtrabilità eritrocitaria e trattamento con pentossifillina.
• PMID: 6673029 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Theobromine
• Pentoxifylline

Topics

• Diabetes Mellitus, Type 1 (blood)
• Diabetic Angiopathies (drug therapy)
• Erythrocytes (physiology)
• Humans
• Middle Aged
• Oxygen Consumption
• Pentoxifylline (therapeutic use)
• Theobromine (analogs & derivatives)
• Ultrafiltration