Abstract |
The effects of progesterone (P) or estradiol benzoate (EB) on unfilled uterine and uterine tubal (oviductal) cytoplasmic estrogen receptors (ER) were studied in nulliparous heifers. Progesterone (4.4 mg/kg of body weight) in oil EB (350 micrograms) in oil, or oil vehicle only (C) were injected IM 24 hours after the end of estrus. The heifers were euthanatized 36 hours later. There was a difference (P less than 0.005) in the concentration of ER among treatment groups, but no difference (P greater than 0.05) between the ER concentrations in the uterus and uterine tube within each treatment group. The affinity constant (KA) of the uterine tubal ER was similar among the treatment groups (P greater than 0.15), and there was no difference (P greater than 0.05) in the KA between the uterus and uterine tubal ER within the P and C treatment groups. The KA of the uterine ER of the EB-treated heifers was greater (P less than 0.001) than that in either P- or C-treated heifers.
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Authors | R O Crisman, L E McDonald, D R Campion, G B Rampacek |
Journal | American journal of veterinary research
(Am J Vet Res)
Vol. 44
Issue 12
Pg. 2246-50
(Dec 1983)
ISSN: 0002-9645 [Print] United States |
PMID | 6660612
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Receptors, Estrogen
- Progesterone
- Estradiol
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Topics |
- Animals
- Cattle
(metabolism, physiology)
- Cytoplasm
(metabolism)
- Estradiol
(pharmacology)
- Fallopian Tubes
(metabolism)
- Female
- Ovum Transport
- Progesterone
(pharmacology)
- Receptors, Estrogen
(drug effects, metabolism)
- Uterus
(metabolism)
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