Alpha-naphthyl butyrate esterase (a selective cytochemical monocyte marker).

Abstract

This paper describes a cytochemical technique for alpha-naphthyl butyrate esterase demonstration in monocytes obtained from peripheral blood of normal subjects, of a patient with reactive monocytosis and of a patient with myelomonocytic leukemia. It utilizes pH 6.1 alpha-naphthyl butyrate as substrate. At this pH value, alpha-naphthyl butyrate is a specific monocyte marker. The cytochemical procedure proposed is simple, rapid and standardized, as it utilizes stable and easily available reagents.

• Authors: U Lippi, P Cappelletti, M Schinella
• Journal: La Ricerca in clinica e in laboratorio (Ric Clin Lab) 1983 Oct-Dec Vol. 13 Issue 4 Pg. 467-71 ISSN: 0390-5748 [Print] Italy
• PMID: 6658305 (Publication Type: Journal Article)

Chemical References

• Carboxylic Ester Hydrolases
• naphthylbutyrate esterase

Topics

• Carboxylic Ester Hydrolases (blood)
• Histocytochemistry
• Humans
• Methods
• Monocytes (enzymology)