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Acute polyarthritis following the use of Corynebacterium parvum vaccine (Coparvax) for malignant pleural effusion.

AbstractA 77-year-old man with a malignant pleural effusion was treated by aspiration of fluid and injection of Corynebacterium parvum vaccine for pleurodesis. Within 24 hr he had developed a temperature and a neutropenia followed by an acute crippling polyarthritis of his hands and wrists which subsequently responded to oral steroids and non-steroidal antiinflammatory drugs.
AuthorsA M Lever, J Forsythe, P Oxford
JournalPostgraduate medical journal (Postgrad Med J) Vol. 59 Issue 698 Pg. 799-800 (Dec 1983) ISSN: 0032-5473 ENGLAND
PMID6657546 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Bacterial Vaccines
Topics
  • Acute Disease
  • Aged
  • Arthritis (etiology)
  • Bacterial Vaccines (adverse effects)
  • Carcinoma, Squamous Cell (therapy)
  • Humans
  • Male
  • Pleural Effusion
  • Pleural Neoplasms (therapy)
  • Propionibacterium acnes (immunology)