HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Thiol compounds in the combined therapy of prozerin poisonings].

Abstract
The authors studied the protective action of dithiols (unithiol, dithiothreitol) and their combinations with atropine in proserine poisoning. With the use of the spatial-prospective plotting the antidote efficacy of dipyroxime, atropine, dithiothreitole, and their combinations was studied and compared. A new type of potentiation was discovered upon combined use of atropine, dipyroxime and dithiothreitol.
AuthorsF P Trinus, T K Riabukha, A V Chubenko, O I Fedotenko
JournalFarmakologiia i toksikologiia (Farmakol Toksikol) 1983 Nov-Dec Vol. 46 Issue 6 Pg. 67-9 ISSN: 0014-8318 [Print] Russia (Federation)
Vernacular TitleTiolovye soedineniia v kombinirovannoĭ terapii otravleniĭ prozerinom.
PMID6653763 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Antidotes
  • Cholinesterase Inhibitors
  • Sulfhydryl Compounds
  • Neostigmine
Topics
  • Animals
  • Antidotes (therapeutic use)
  • Cholinesterase Inhibitors (poisoning)
  • Dose-Response Relationship, Drug
  • Drug Evaluation, Preclinical
  • Drug Synergism
  • Drug Therapy, Combination
  • Neostigmine (poisoning)
  • Rats
  • Sulfhydryl Compounds (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: