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Studies on chemotherapy of parasitic helminths (XVIII). Mechanism of spastically paralyzing action of pyrantel in Angiostrongylus cantonensis.

Abstract
Pyrantel tartrate caused spastic paralysis through stimulating nicotinic cholinoceptors in Angiostrongylus cantonensis.
AuthorsM Terada, A I Ishii, H Kino, M Sano
JournalExperientia (Experientia) Vol. 39 Issue 12 Pg. 1383-5 (Dec 15 1983) ISSN: 0014-4754 [Print] Switzerland
PMID6653728 (Publication Type: Journal Article)
Chemical References
  • Receptors, Nicotinic
  • Pyrantel
  • gamma-Aminobutyric Acid
  • Pyrantel Tartrate
  • Tubocurarine
Topics
  • Angiostrongylus (physiology)
  • Animals
  • Female
  • Metastrongyloidea (physiology)
  • Movement (drug effects)
  • Nematode Infections (drug therapy)
  • Pyrantel (analogs & derivatives)
  • Pyrantel Tartrate (pharmacology, therapeutic use)
  • Rats
  • Receptors, Nicotinic (drug effects)
  • Tubocurarine (pharmacology)
  • gamma-Aminobutyric Acid (pharmacology)

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