[Effect of adrenalectomy and chemical sympathectomy on the catecholamines content in the central nervous system in hemorrhagic stress].

Abstract

Content of adrenaline, noradrenaline, dopamine and normetanephrine was estimated by means of trihydroxyindole method in samples of brain and its hypothalamic part from intact, adrenal- and sympathectomized rats within 15 min, 24 and 72 hrs after hemorrhagic stress (3% blood of body weight within 20 min). Stable increase in dopamine content was observed in brain at all the periods studied. Alterations in the noradrenaline turnover in central nervous system were related to the state of peripheral sympathoadrenal system at early posthemorrhagic steps; the phenomenon was not found at the later periods after stress.

• Authors: E A Shirinian, O M Avakian
• Journal: Voprosy meditsinskoi khimii (Vopr Med Khim) 1978 Mar-Apr Vol. 24 Issue 2 Pg. 216-9 ISSN: 0042-8809 [Print] Russia (Federation)
• Vernacular Title: Vliianie adrenaléktomii i khimicheskoĭ simpatéktomii na soderzhanie katekholaminov v tsentral'noĭ nervnoĭ sisteme pri gemorragicheskom stresse.
• PMID: 664447 (Publication Type: English Abstract, Journal Article)

Chemical References

• Catecholamines
• Normetanephrine
• Dopamine
• Norepinephrine
• Epinephrine

Topics

• Adrenal Glands (physiology)
• Adrenalectomy
• Animals
• Catecholamines (metabolism)
• Central Nervous System (metabolism)
• Dopamine (metabolism)
• Epinephrine (metabolism)
• Hemorrhage (metabolism)
• Male
• Norepinephrine (metabolism)
• Normetanephrine (metabolism)
• Rats
• Stress, Physiological (metabolism)
• Sympathetic Nervous System (drug effects)
• Time Factors