Improved exercise myocardial perfusion during lidoflazine therapy.

Abstract

Lidoflazine is a synthetic drug with calcium-channel blocking effects. In a study of 6 patients with severe classic angina pectoris, single-blind administration of lidoflazine was associated with improved myocardial perfusion during exercise as determined by thallium-201 stress scintigraphy. These studies demonstrate that lidoflazine therapy is associated with relief of angina, an increased physical work capacity, and improved regional myocardial perfusion during exercise.

• Authors: W Shapiro, K A Narahara, J Park
• Journal: Angiology (Angiology) Vol. 34 Issue 11 Pg. 705-10 (Nov 1983) ISSN: 0003-3197 [Print] United States
• PMID: 6638605 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Piperazines
• Radioisotopes
• Thallium
• Lidoflazine

Topics

• Adult
• Angina Pectoris (drug therapy)
• Electrocardiography
• Heart Rate (drug effects)
• Humans
• Lidoflazine (therapeutic use)
• Middle Aged
• Perfusion
• Physical Exertion
• Piperazines (therapeutic use)
• Radioisotopes
• Thallium