[General control of amino acid biosynthesis in mutants of Candida spec. EH 15/D].

Abstract

The general control of amino acid biosynthesis was investigated in Candida spec. EH 15/D, using single and double mutant auxotrophic strains and prototrophic revertants starved for their required amino acids. These experiments show that starvation for lysine, histidine, arginine, leucine, threonine, proline, serine, methionine, homoserine, asparagine, glutamic acid or aspartic acid can result in derepression of enzymes. A correlation was found between the degree of derepression, growth of strains, and concentration of required amino acids. The amino acids pool pattern of mutants and revertants is different from that in the wild type strain.

• Authors: R Bode, P Casper
• Journal: Zeitschrift fur allgemeine Mikrobiologie (Z Allg Mikrobiol) Vol. 23 Issue 7 Pg. 419-27 ( 1983) ISSN: 0044-2208 [Print] Germany
• Vernacular Title: Allgemeine Kontrolle der Aminosäurebiosynthese in Mutanten von Candida spec. EH 15/D.
• PMID: 6636844 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Amino Acids

Topics

• Amino Acids (biosynthesis)
• Candida (genetics, growth & development, metabolism)
• Kinetics
• Mutation