Alteration in natural resistance of sarcoma 180 tumor to Bouvardin (NSC 259968) following hyperthermia.

Abstract	Sarcoma-180 (S-180) tumor cells grown in Swiss mice displayed natural resistance to Bouvardin (NSC 259968) when administered alone in a single dose or in multiple doses. Hyperthermia treatment (43 degrees C for 1 hr) alone did not show any tumor growth reduction. However, the drug combined with hyperthermia markedly reduced tumor growth suggesting that hyperthermia alters the natural resistance of S-180 cells to Bouvardin.
Authors	M K Adwankar, M P Chitnis
Journal	Tumori (Tumori) Vol. 69 Issue 4 Pg. 309-12 (Aug 31 1983) ISSN: 0300-8916 [Print] United States
PMID	6623654 (Publication Type: Comparative Study, Journal Article)
Chemical References	Antineoplastic Agents, Phytogenic Peptides, Cyclic bouvardin
Topics	Animals Antineoplastic Agents, Phytogenic (administration & dosage) Combined Modality Therapy Drug Evaluation, Preclinical Drug Resistance Hyperthermia, Induced Mice Mice, Inbred Strains Peptides, Cyclic (administration & dosage) Sarcoma 180 (therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!