[Clinical study on T-1982 (cefbuperazone) in the field of obstetrics and gynecology].

Abstract

A clinical investigation on the efficacy of T-1982 (cefbuperazone), a new cephamycin antibiotic, was performed in the field of obstetrics and gynecology. T-1982 was administered to 17 cases: 6 cases of parametritis, 3 cases of endometritis after artificial abortion, 3 cases of puerperal fever, 2 cases of febrile abortion, 1 case of Bartholin's abscess, 1 case of adnexitis and 1 case of infection of vaginal hematoma. Seventeen cases of these infections receiving in total 6 to 20 g of T-1982 demonstrated excellent results in 8 cases and good in the remaining 9 cases. Neither side effect nor clinical test abnormality was observed. From the present study, T-1982 is considered to have excellent efficacy and safety.

• Authors: S Hori, N Hosoi, I Makino, Y Inaba
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 36 Issue 5 Pg. 976-81 (May 1983) ISSN: 0368-2781 [Print] Japan
• PMID: 6620565 (Publication Type: Journal Article)

Chemical References

• Cephamycins
• cefbuperazone

Topics

• Adult
• Aged
• Cephamycins (therapeutic use)
• Endometritis (drug therapy)
• Female
• Humans
• Middle Aged
• Pelvic Inflammatory Disease (drug therapy)
• Peritonitis (drug therapy)
• Pregnancy
• Puerperal Infection (drug therapy)