Susceptibility of Bacteroides nodosus to various antimicrobial agents.

Abstract

The susceptibility of 18 strains of Bacteroides nodosus to 21 antimicrobial agents was tested in vitro. Penicillin was the most effective antibiotic tested. Other antibiotics tested, in order of relative efficacy, were cefamandole, clindamycin, tetracycline, chloramphenicol, erythromycin, sodium cefoxitin, tylosin tartrate, nitrofurazone, tinidazole, and dihydrostreptomycin sulfate. Tests of solutions of 4 antibiotics in 70% ethanol indicated that ethanol served primarily as a diluent and did not contribute substantially to the curative effect of such topical medications on foot rot lesions in sheep. Of the chemicals commonly used in foot baths for treatment of ovine foot rot, copper sulfate was most effective, followed by zinc sulfate, then formalin. Several commercial disinfectants and iodine were quite effective against B nodosus, whereas 5.25% sodium hypochlorite and 70% ethanol alone were relatively ineffective.

• Authors: J L Gradin, J A Schmitz
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 183 Issue 4 Pg. 434-7 (Aug 15 1983) ISSN: 0003-1488 [Print] United States
• PMID: 6618969 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Anti-Bacterial Agents
• Sulfates
• Formaldehyde
• Zinc Sulfate
• Copper
• Zinc
• Copper Sulfate

Topics

• Animals
• Anti-Bacterial Agents (pharmacology, therapeutic use)
• Bacteroides (drug effects)
• Bacteroides Infections (drug therapy, veterinary)
• Copper (pharmacology)
• Copper Sulfate
• Foot Rot (drug therapy, etiology)
• Formaldehyde (pharmacology)
• Microbial Sensitivity Tests
• Sheep
• Sheep Diseases (drug therapy, etiology)
• Sulfates (pharmacology)
• Zinc (pharmacology)
• Zinc Sulfate