Labelling pattern of the nonhistone chromosomal proteins in quiescent and dividing Ehrlich ascites tumour cells.

Abstract

Upon pulse-labelling with [14C]protein hydrolizate both in dividing and quiescent Ehrlich ascites tumour (EAT) cells the nonhistone chromosomal (NHC) proteins had uniform specific radioactivity with few exceptions: Both in quiescent and dividing EAT cells a polypeptide with molecular weight of about 200 kdalton had specific radioactivity 2-3 times lower than that of the most of the NHC proteins. In the actively proliferating cells a group of proteins with molecular weights between 45 and 65 kdalton had 2-3 times higher specific radioactivity than most of the NHC proteins. In quiescent cells the specific radioactivity of a group of proteins with molecular weights in the range 18-25 kdalton was 3-4 times higher than that of the rest of the NHC proteins.

• Authors: B Anachkova, G Russev
• Journal: The International journal of biochemistry (Int J Biochem) Vol. 15 Issue 8 Pg. 1093-4 ( 1983) ISSN: 0020-711X [Print] England
• PMID: 6617954 (Publication Type: Journal Article)

Chemical References

• Chromosomal Proteins, Non-Histone

Topics

• Animals
• Carcinoma, Ehrlich Tumor (metabolism)
• Cell Division
• Chromosomal Proteins, Non-Histone (metabolism)
• Mice
• Molecular Weight