Abstract |
Two siblings who developed adult T-cell leukemia (ATL) with unusual clinical courses are presented. The brother showed spontaneous remissions at the beginning stage of the disease of 6 years' duration, and the sister remains free of complaints for 6 years without chemotherapy. The patients and 2 of 12 healthy members of their family examined had serum antibodies against ATL-associated antigens (ATLA). The expression of ATLA was observed in the cultured lymphocytes from the patients and one of the family members.
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Authors | F Kawano, H Tsuda, K Yamaguchi, H Nishimura, I Sanada, H Matsuzaki, M Ishii, K Takatsuki |
Journal | Cancer
(Cancer)
Vol. 54
Issue 1
Pg. 131-4
(Jul 01 1984)
ISSN: 0008-543X [Print] United States |
PMID | 6609759
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Membrane Glycoproteins
- thymus-leukemia antigens
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Topics |
- Antibodies, Monoclonal
- Antigens, Neoplasm
(analysis)
- Cell Separation
- Female
- Humans
- Leukemia
(genetics, immunology, pathology)
- Male
- Membrane Glycoproteins
- Middle Aged
- Pedigree
- T-Lymphocytes
(immunology, pathology)
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