Pancreolauryl test. Evaluation of a tubeless pancreatic function test in comparison with other indirect and direct tests for exocrine pancreatic function.

Abstract

The sensitivity and specificity of the pancreolauryl test was evaluated in comparison with the NBT-PABA test, the estimation of fecal chymotrypsin and fat, and the secretin-pancreozymin test in 168 patients with and without pancreatic disease. The overall sensitivity rate was as follows: pancreolauryl test 90%, NBT-PABA test 86%, fecal chymotrypsin 66%. In patients with pancreatic steatorrhea the sensitivity of the pancreolauryl test was 100%, the NBT-PABA test 97%, and the fecal chymotrypsin estimation 92%. The specificity of these tests was: pancreolauryl test 97.6%, fecal chymotrypsin 87%, and NBT-PABA test 81.8%. The pancreolauryl test may be recommended as a noninvasive easy-to-perform tubeless pancreatic function test with a sufficiently high sensitivity and specificity.

• Authors: P G Lankisch, A Schreiber, J Otto
• Journal: Digestive diseases and sciences (Dig Dis Sci) Vol. 28 Issue 6 Pg. 490-3 (Jun 1983) ISSN: 0163-2116 [Print] United States
• PMID: 6602697 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Fluoresceins
• Secretin
• Nitroblue Tetrazolium
• Cholecystokinin
• fluorescein dilaurate
• Chymotrypsin
• 4-Aminobenzoic Acid

Topics

• 4-Aminobenzoic Acid
• Cholecystokinin
• Chronic Disease
• Chymotrypsin (analysis)
• Feces (analysis)
• Fluoresceins
• Humans
• Nitroblue Tetrazolium
• Pancreatic Function Tests
• Pancreatitis (diagnosis)
• Secretin