Progressive hemifacial atrophy (Parry-Romberg syndrome) report with review of genetics and nosology.

Abstract

We describe a boy with mild hemifacial atrophy (Parry-Romberg syndrome); he had localized scleroderma on a leg and his trunk, and antinuclear antibodies in his serum. These findings support suggestions that this disorder could be a variant of localized scleroderma rather than a developmental anomaly or dysplasia. A review of the literature does not support assertions of autosomal dominant inheritance of the condition.

• Authors: R M Lewkonia, R B Lowry
• Journal: American journal of medical genetics (Am J Med Genet) Vol. 14 Issue 2 Pg. 385-90 (Feb 1983) ISSN: 0148-7299 [Print] United States
• PMID: 6601461 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Antinuclear

Topics

• Adolescent
• Antibodies, Antinuclear (analysis)
• Facial Hemiatrophy (classification, genetics)
• Genes, Dominant
• Genetic Variation
• Humans
• Male
• Scleroderma, Localized (classification, genetics)
• Syndrome
• Terminology as Topic