Chemotherapy in porphyria.

Abstract

The clinical courses of 5 patients with hepatic porphyrias (4 with porphyria variegata) who required chemotherapy for disseminated malignant diseases are reviewed. Antineoplastic agents were employed without evidence that these drugs precipitated porphyric crises. It is concluded that the chemotherapeutic approach to these patients should be based on the appropriate treatment for the malignant condition.

• Authors: B Samuels, W R Bezwoda, D P Derman, G Goss
• Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (S Afr Med J) Vol. 65 Issue 23 Pg. 924-6 (Jun 09 1984) ISSN: 0256-9574 [Print] South Africa
• PMID: 6587589 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Acute Disease
• Adolescent
• Adult
• Breast Neoplasms (complications)
• Female
• Humans
• Leukemia, Lymphoid (complications)
• Liver Diseases (complications, drug therapy)
• Lymphoma, Non-Hodgkin (complications)
• Middle Aged
• Porphyrias (complications, drug therapy)