Inhibition of glycolysis by L-sorbose in dog erythrocytes.

Abstract	We have demonstrated previously that in vitro L-sorbose acts directly on dog erythrocytes to induce hemolysis. Here we report that L-sorbose depresses lactate formation in dog hemolysates from glucose, mannose and fructose but not from glucose-6-phosphate and galactose, suggesting that L-sorbose interacts with glycolysis at the level of the hexokinase.
Authors	A Kistler, P Keller
Journal	Experientia (Experientia) Vol. 34 Issue 6 Pg. 800-2 (Jun 15 1978) ISSN: 0014-4754 [Print] Switzerland
PMID	658309 (Publication Type: Journal Article)
Chemical References	Blood Glucose Glucosephosphates Fructose Sorbose Mannose
Topics	Animals Blood Glucose Dogs Erythrocytes (metabolism) Fructose (blood) Galactosemias Glucosephosphates (blood) Glycolysis (drug effects) Hemolysis In Vitro Techniques Mannose (blood) Sorbose (pharmacology)

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