Abstract |
Chronic myelogenous leukemia was diagnosed in 7 dogs. In each case, marked neutrophilia in the absence of infection was observed in association with nonspecific illness. Diagnosis was based on morphologic cytology of blood smears, bone marrow aspirates, and in 1 case, a lymph node biopsy specimen. In 5 cases, treatment with hydroxyurea was successful in lowering circulating WBC counts, but was of questionable value in the prevention of leukemic blast crisis.
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Authors | C E Leifer, R E Matus, A K Patnaik, E G MacEwen |
Journal | Journal of the American Veterinary Medical Association
(J Am Vet Med Assoc)
Vol. 183
Issue 6
Pg. 686-9
(Sep 15 1983)
ISSN: 0003-1488 [Print] United States |
PMID | 6579047
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Animals
- Biopsy, Needle
- Blood Cell Count
(veterinary)
- Bone Marrow
(pathology)
- Cytodiagnosis
(veterinary)
- Dog Diseases
(diagnosis, drug therapy)
- Dogs
- Drug Therapy, Combination
- Female
- Hydroxyurea
(therapeutic use)
- Leukemia, Myeloid
(diagnosis, drug therapy, veterinary)
- Lymph Nodes
(pathology)
- Male
- Oxymetholone
(therapeutic use)
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