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Chronic myelogenous leukemia in the dog.

Abstract
Chronic myelogenous leukemia was diagnosed in 7 dogs. In each case, marked neutrophilia in the absence of infection was observed in association with nonspecific illness. Diagnosis was based on morphologic cytology of blood smears, bone marrow aspirates, and in 1 case, a lymph node biopsy specimen. In 5 cases, treatment with hydroxyurea was successful in lowering circulating WBC counts, but was of questionable value in the prevention of leukemic blast crisis.
AuthorsC E Leifer, R E Matus, A K Patnaik, E G MacEwen
JournalJournal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 183 Issue 6 Pg. 686-9 (Sep 15 1983) ISSN: 0003-1488 [Print] United States
PMID6579047 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Oxymetholone
  • Hydroxyurea
Topics
  • Animals
  • Biopsy, Needle
  • Blood Cell Count (veterinary)
  • Bone Marrow (pathology)
  • Cytodiagnosis (veterinary)
  • Dog Diseases (diagnosis, drug therapy)
  • Dogs
  • Drug Therapy, Combination
  • Female
  • Hydroxyurea (therapeutic use)
  • Leukemia, Myeloid (diagnosis, drug therapy, veterinary)
  • Lymph Nodes (pathology)
  • Male
  • Oxymetholone (therapeutic use)

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