Clinical evaluation of cefotetan in the treatment of lower respiratory tract infections.

Abstract

Cefotetan, a new cephamycin antibiotic, was evaluated for the treatment of lower respiratory tract infections. Intravenous cefotetan (2 g every 12 h) was administered for 4 to 8 days (mean, 5.8 days) to 56 hospitalized adult patients. Of the 41 evaluable patients, the clinical response was satisfactory in 38 (93%) and the bacteriological response was satisfactory in 36 (88%). The drug was well tolerated, and there were minimal complaints or changes in clinical laboratory values. From these preliminary results, cefotetan appears to be safe and effective for the treatment of lower respiratory tract infections.

• Authors: T M Nolen, H L Phillips, H J Hall
• Journal: The Journal of antimicrobial chemotherapy (J Antimicrob Chemother) Vol. 11 Suppl Pg. 233-6 (Jan 1983) ISSN: 0305-7453 [Print] England
• PMID: 6573322 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Cephalosporins
• Cephamycins
• Cefotetan

Topics

• Adult
• Aged
• Anti-Bacterial Agents (therapeutic use)
• Cefotetan
• Cephalosporins (therapeutic use)
• Cephamycins (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Respiratory Tract Infections (drug therapy)