Influenza A/Philippines/2/82 outbreak in a nursing home: limitations of influenza vaccination in the aged.

Abstract

The failure of the 1982-1983 influenza vaccine to protect elderly NHCU residents from clinical infection with influenza A/Philippines/2/82 resulted primarily from antigenic drift of the epidemic strain, inasmuch as the attack rates in the vaccinated and nonvaccinated patients were not significantly different. This experience supports the decision to replace A/Bangkok/1/79 with A/Philippines/2/82 virus antigen in the 1983-1984 influenza vaccine.

• Authors: J C Arroyo, B Postic, A Brown, K Harrison, R Birgenheier, H Dowda
• Journal: American journal of infection control (Am J Infect Control) Vol. 12 Issue 6 Pg. 329-34 (Dec 1984) ISSN: 0196-6553 [Print] United States
• PMID: 6569790 (Publication Type: Journal Article)

Chemical References

• Antibodies, Viral
• Antigens, Viral
• Influenza Vaccines

Topics

• Adult
• Age Factors
• Aged
• Antibodies, Viral (analysis)
• Antigens, Viral (immunology)
• Cross Infection (epidemiology)
• Disease Outbreaks (prevention & control)
• Female
• Humans
• Influenza A virus (immunology)
• Influenza Vaccines
• Influenza, Human (epidemiology, immunology, prevention & control)
• Male
• Middle Aged
• Nursing Homes
• Patient Isolation
• South Carolina
• Vaccination