A double-blind controlled evaluation of the nasal decongestant effect of Day Nurse in the common cold.

Abstract

A rhinomanometric technique was used to evaluate the nasal decongestant effect of a single dose of Day Nurse over a 4-hour post-dosing period in human volunteers suffering from nasal congestion due to a common cold. A significant improvement in nasal congestion was obtained at the 1 hour, 2 hour, 3 hour and 4 hour post-dosing interval, from initial values compared to a placebo group. The study therefore demonstrated by an objective technique that Day Nurse provides relief of nasal congestion and related symptoms in cold sufferers.

• Authors: P Lea
• Journal: The Journal of international medical research (J Int Med Res) Vol. 12 Issue 2 Pg. 124-7 ( 1984) ISSN: 0300-0605 [Print] England
• PMID: 6547101 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Drug Combinations
• Multi-Ingredient Cold, Flu, and Allergy Medications
• acetaminophen, pholcodine, pseudoephedrine drug combination
• Levorphanol
• Phenylpropanolamine
• Acetaminophen
• Dextromethorphan
• Pseudoephedrine
• Ascorbic Acid
• Codeine

Topics

• Acetaminophen (therapeutic use)
• Adolescent
• Adult
• Aged
• Ascorbic Acid (therapeutic use)
• Codeine (analogs & derivatives)
• Common Cold (drug therapy, physiopathology)
• Dextromethorphan (therapeutic use)
• Double-Blind Method
• Drug Combinations (therapeutic use)
• Female
• Humans
• Levorphanol (analogs & derivatives)
• Male
• Manometry
• Middle Aged
• Multi-Ingredient Cold, Flu, and Allergy Medications
• Nose (physiopathology)
• Phenylpropanolamine (therapeutic use)
• Pressure
• Pseudoephedrine
• Random Allocation
• Time Factors