Abstract |
Twenty-one families with familial Alzheimer disease were ascertained in a dementia clinic and assessed by multiple family interviews. Eight autopsies were reviewed. The age of onset varied from 25 to 85. Seven pedigrees showed evidence of 3 generation transmission. Paternal age of the founders of 4 lines which could be assessed was higher than controls.
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Authors | D Powell, M F Folstein |
Journal | Journal of neurogenetics
(J Neurogenet)
Vol. 1
Issue 2
Pg. 189-97
(Apr 1984)
ISSN: 0167-7063 [Print] England |
PMID | 6536726
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Topics |
- Adult
- Age Factors
- Aged
- Alzheimer Disease
(genetics)
- Female
- Genes, Dominant
- Humans
- Male
- Middle Aged
- Pedigree
- Sex Factors
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