[Metabolic disorders and functional properties of erythrocytes in acute arterial obstruction of the extremities].

Abstract

On the basis of experimental studies (in 43 rabbits) of the model of acute arterial obstruction and examination of 19 patients with various kinds of acute ischemia of the extremity it was established that the development of the ischemic lesions of the extremity can result in significant changes in the metabolism of adenyl nucleotides and deformability of erythrocytes. The value of the erythrocytes deformability gradient can show the degree of reversibility of ischemia of the diseased extremity.

• Authors: M L Kliachkin, N B Zakharova
• Journal: Vestnik khirurgii imeni I. I. Grekova (Vestn Khir Im I I Grek) Vol. 133 Issue 12 Pg. 37-9 (Dec 1984) ISSN: 0042-4625 [Print] Russia (Federation)
• Vernacular Title: Narusheniia metabolizma i funktsional'nye svoĭstva éritrotsitov pri ostroĭ arterial'noĭ neprokhodimosti konechnosti.
• PMID: 6528436 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adenine Nucleotides

Topics

• Acute Disease
• Adenine Nucleotides (blood)
• Animals
• Arterial Occlusive Diseases (physiopathology)
• Erythrocyte Deformability
• Erythrocytes (metabolism)
• Extremities (blood supply)
• Glycolysis
• Humans
• Ischemia (physiopathology)
• Leg (blood supply)
• Rabbits