Clinical trial of thiamphenicol therapy for uncomplicated gonorrhea.

Abstract

The need for a safe drug that is easy to administer and not too expensive prompted a study of treatment of uncomplicated gonorrhea with a single oral dose of 2.5 g of thiamphenicol. Of 169 patients treated, 161 were cured. Of the 92 patients with acute infections, all of the 13 men and 74 (93.7%) of the 79 women were cured. Seventy-seven cases were defined as reinfection; all of the 22 men in this group were cured, as were 52 (94.5%) of the 55 women. Only minor adverse effects were noted. It is concluded that thiamphenicol is a safe and effective antibiotic for therapy of uncomplicated gonorrhea.

• Authors: C S De Parra, H L Cortés, J S Medina
• Journal: Sexually transmitted diseases (Sex Transm Dis) 1984 Oct-Dec Vol. 11 Issue 4 Suppl Pg. 423-5 ISSN: 0148-5717 [Print] United States
• PMID: 6523322 (Publication Type: Journal Article)

Chemical References

• Solutions
• Thiamphenicol

Topics

• Administration, Oral
• Adolescent
• Adult
• Drug Evaluation
• Female
• Gonorrhea (drug therapy)
• Humans
• Male
• Solutions
• Thiamphenicol (administration & dosage)