[Immunogenetic characteristics of patients with ischemic heart disease].

Abstract

The distribution of the principal erythrocyte and HLA-antigens was investigated in 202 males aged 20-50 years with a history of myocardial infarction and various courses of coronary heart disease. The occurrence of one or the other group of antigens differed both as compared with a group of healthy subjects (619 subjects) and in relation to the anamnestic and clinical characteristics of the disease course. The findings helped to draw a conclusion as to the presence of associative links between a number of the studied antigens (A (II), MN, HLA-B7, HLA-B14, HLA-B15, HLA-CW4) and the risk of the development of, at least, some forms of coronary heart disease.

• Authors: M F Balliuzek, L D Serova, B B Bondarenko
• Journal: Kardiologiia (Kardiologiia) Vol. 24 Issue 10 Pg. 77-81 (Oct 1984) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Immunogeneticheskaia kharakteristika bol'nykh ishemicheskoĭ bolezn'iu serdtsa.
• PMID: 6521189 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Blood Group Antigens
• HLA Antigens

Topics

• Adult
• Blood Group Antigens (immunology)
• Coronary Disease (etiology, genetics, immunology)
• HLA Antigens (analysis, genetics)
• Humans
• Immunity, Innate
• Male
• Middle Aged