HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Lack of synergistic effect between arsenic, mercury and ethyl methane sulfonate on the frequency of chromosomal aberrations in mice.

Abstract
The influence of arsenic and mercury on the frequency of chromosome aberrations induced by ethylmethane sulfonate was studied in mice. No synergistic effects could be demonstrated in somatic and germ cells of mice given a combined treatment of arsenic trioxide solution (As2O3, 12 mg per kg body weight) or of mercuric chloride solution (HgCl2, 6 mg per kg body weight) with ethylmethane sulfonate (EMS, 200 mg per kg body weight).
AuthorsK Poma, M Kirsch-Volders, C Susanne, N Degraeve
JournalJournal of applied toxicology : JAT (J Appl Toxicol) Vol. 4 Issue 6 Pg. 293-6 (Dec 1984) ISSN: 0260-437X [Print] England
PMID6520317 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Ethyl Methanesulfonate
  • Mercury
  • Arsenic
Topics
  • Animals
  • Arsenic (toxicity)
  • Bone Marrow (ultrastructure)
  • Chromosome Aberrations
  • Drug Synergism
  • Ethyl Methanesulfonate (toxicity)
  • Male
  • Mercury (toxicity)
  • Mice
  • Spermatogonia (ultrastructure)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: