Abstract |
The safety of topical selenium sulfide lotion in man has been demonstrated previously. Twenty male patients with a diagnosis of tinea versicolor were randomly assigned to two parallel groups who applied selenium sulfide lotion or the vehicle to the entire skin surface, excluding mucous membranes, for 10 minutes once daily for 7 consecutive days. Blood and urine selenium levels were determined before and after treatment and showed no significant differences between the active drug and vehicle groups on any study day. It would appear that no significant absorption of selenium took place as a result of this treatment regimen.
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Authors | J L Sánchez, V M Torres |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 11
Issue 2 Pt 1
Pg. 238-41
(Aug 1984)
ISSN: 0190-9622 [Print] United States |
PMID | 6480923
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Selenium Compounds
- Selenium
- selenium disulfide
|
Topics |
- Administration, Topical
- Adolescent
- Adult
- Humans
- Male
- Middle Aged
- Selenium
(administration & dosage, blood, urine)
- Selenium Compounds
- Skin Absorption
- Tinea Versicolor
(metabolism)
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