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[Wound cleansing with the enzyme combination fibrinolysin/deoxy-ribonuclease].

Abstract
This clinical investigation was performed to evaluate the therapeutic efficacy of enzymatic wound débridement. Fibrolan (Elase), a combination of fibrinolysin and desoxyribonuclease, was administered in 42 patients with infected accidental or operation wounds. After a treatment over 12 to 14 days all but two wounds showed clean granulation tissue and secondary wound closure could be achieved. There was no sign of adverse drug reaction. A recommendation of this method in the treatment of infected wounds can be given.
AuthorsN Schwarz
JournalFortschritte der Medizin (Fortschr Med) Vol. 99 Issue 25 Pg. 978-80 (Jul 02 1981) ISSN: 0015-8178 [Print] Germany
Vernacular TitleErfahrungen bei der Wundreinigung mit der Enzym-Kombination Fibrinolysin/Desoxyribonuklease.
PMID6455371 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Ointments
  • Deoxyribonucleases
  • Fibrinolysin
Topics
  • Adolescent
  • Adult
  • Aged
  • Child
  • Deoxyribonucleases (therapeutic use)
  • Drug Therapy, Combination
  • Fibrinolysin (therapeutic use)
  • Humans
  • Leg Ulcer (drug therapy)
  • Middle Aged
  • Ointments
  • Surgical Wound Infection (drug therapy)
  • Wound Healing (drug effects)
  • Wound Infection (drug therapy)

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