Successful treatment of keratoderma hereditaria mutilans with an aromatic retinoid.

Abstract

Clinical features and treatment of keratoderma hereditaria mutilans (Vohwinkel's syndrome) are described in an 11-year-old boy. The disease, in particular the mutilating complications (pseudo-ainhum), responded satisfactorily to the oral administration of etretinate, an aromatic retinoid.

• Authors: A F Chang Sing Pang, A P Oranje, V D Vuzevki, E Stolz
• Journal: Archives of dermatology (Arch Dermatol) Vol. 117 Issue 4 Pg. 225-8 (Apr 1981) ISSN: 0003-987X [Print] United States
• PMID: 6452098 (Publication Type: Case Reports, Journal Article)

Chemical References

• Tretinoin
• Etretinate

Topics

• Administration, Oral
• Ainhum (drug therapy, pathology)
• Child
• Constriction, Pathologic (drug therapy, pathology)
• Edema (drug therapy)
• Etretinate (administration & dosage, therapeutic use)
• Humans
• Keratoderma, Palmoplantar (drug therapy, pathology)
• Male
• Pigmentation Disorders (drug therapy)
• Syndrome
• Tretinoin (analogs & derivatives)