[Effect of a tissue oxygenator (almitrine + raubasine) on the metabolism of 2,3-diphosphoglycerate of rabbits submitted by hypoxia]

• Abstract: In normoxic rabbits, the intravenous injection (1 mg/kg) of the product (almitrine + raubasine) do not modify the erythrocytic level of 2,3-DPG. But, after hypoxia (the rabbits being submitted to an oxygen pressure of 7,8 kPa during 20 minutes) the same dose of this product induce a durable rise of erythrocytic 2,3-DPG level which remain, 24 hours latter, + 15% above normal.
• Authors: A Callis, M Dorance, B Magnan de Bornier
• Journal: Comptes rendus des séances de la Société de biologie et de ses filiales (C R Seances Soc Biol Fil) Vol. 174 Issue 6 Pg. 1006-9 ( 1980) ISSN: 0037-9026 [Print] FRANCE
• Vernacular Title: Effet d'un oxygénateur tissulaire (almitrine + raubasine) sur le métabolisme du 2,3-diphosphoglycérate du lapin soumis à une hypoxie.
• PMID: 6451260 (Publication Type: English Abstract, Journal Article)

Chemical References

• Diphosphoglyceric Acids
• Piperazines
• Secologanin Tryptamine Alkaloids
• Triazines
• Yohimbine
• Almitrine
• ajmalicine
• Oxygen

Topics

• Almitrine
• Animals
• Anoxia (blood)
• Diphosphoglyceric Acids (blood)
• Erythrocytes (drug effects, metabolism)
• Kinetics
• Oxygen (blood)
• Partial Pressure
• Piperazines (pharmacology)
• Rabbits
• Secologanin Tryptamine Alkaloids
• Triazines (pharmacology)
• Yohimbine (pharmacology)