Allergic contact dermatitis from methylisothiocyanate in soil disinfectants.

Abstract

Observations on nine patients with occupational dermatitis from methylisothiocyanate (MITC) lead to the following conclusions: 1. MITC causes primarily a toxic dermatitis, but as a strong sensitizer it induces sensitization as well. 2. Cross reactions between MITC and benzylisothiocyanate, the active agent of Sulbentin antimycotics, were not seen. 3. In patient a MITC acid burn on one foot and leg caused systemic poisoning from absorption with reversible damage to the liver parenchyma.

• Authors: G Richter
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 6 Issue 3 Pg. 183-6 (Apr 1980) ISSN: 0105-1873 [Print] England
• PMID: 6446434 (Publication Type: Case Reports, Journal Article)

Chemical References

• Disinfectants
• Isothiocyanates
• Soil
• Thiocyanates
• methyl isothiocyanate

Topics

• Adult
• Burns, Chemical (etiology)
• Chemical and Drug Induced Liver Injury
• Dermatitis, Contact (etiology)
• Dermatitis, Occupational (chemically induced)
• Disinfectants (adverse effects, poisoning)
• Female
• Humans
• Isothiocyanates
• Soil
• Thiocyanates (adverse effects, poisoning)