Prevalence and pathogenesis of impotence in one hundred uremic men.

Abstract

In a study of dialysis patients 79% of men complained of sexual dysfunction and 61% erectile impotence following uremia and the onset of regular dialysis therapy. Plasma testosterone levels were significantly higher in patients treated by continuous ambulatory peritoneal dialysis (p = 0.001) but the incidence of sexual dysfunction was not different from patients treated by hemodialysis. Although follicle-stimulating hormone levels were higher (p = 0.001) and penile blood pressure index levels lower (p less than 0.05) in patients with impotence, sexual function was not improved by exogenous testosterone, and vasculogenic impotence was identified in only 6% of patients. These findings suggest that a major component of uremic impotence is unrelated to primary testicular failure or penile vascular insufficiency.

• Authors: R S Rodger, K Fletcher, J H Dewar, D Genner, M McHugh, R Wilkinson, M K Ward, D N Kerr
• Journal: Uremia investigation (Uremia Invest) 1984-1985 Vol. 8 Issue 2 Pg. 89-96 ISSN: 0740-1353 [Print] United States
• PMID: 6443249 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Testosterone
• Prolactin
• Luteinizing Hormone
• Follicle Stimulating Hormone
• Zinc

Topics

• Adult
• Aged
• Erectile Dysfunction (etiology)
• Follicle Stimulating Hormone (blood)
• Gynecomastia (complications)
• Humans
• Kidney Failure, Chronic (complications)
• Luteinizing Hormone (blood)
• Male
• Middle Aged
• Penis (blood supply)
• Peritoneal Dialysis
• Prolactin (blood)
• Renal Dialysis
• Testis (pathology)
• Testosterone (blood)
• Uremia (complications)
• Zinc (blood)