[Antitumor activity of Lactobacillus casei YIT 9018 (LC 9018)--effect of administration route].

Abstract

Antitumor activity of lactobacilli on Sarcoma 180 was investigated and was shown to be different from strain to strain. In general, Lactobacillus casei had higher antitumor activity compared with other species of lactobacilli. Among these, L. casei YIT 9018 (LC 9018) had significant antitumor activity against Meth A fibrosarcoma when administered into BALB/c mice intravenously, intraperitoneally, subcutaneously, intratumorally or orally. LC 9018 showed antitumor activity against rat ascites hepatoma by intravenous or oral administration, but this activity was lower than that against Meth A in mice.

• Authors: T Yokokura, I Kato, T Matsuzaki, M Mutai, H Satoh
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 11 Issue 11 Pg. 2427-33 (Nov 1984) ISSN: 0385-0684 [Print] Japan
• PMID: 6437346 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic

Topics

• Adjuvants, Immunologic (administration & dosage, therapeutic use)
• Animals
• Killer Cells, Natural (immunology)
• Lacticaseibacillus casei
• Liver Neoplasms, Experimental (immunology, therapy)
• Male
• Mice
• Mice, Inbred BALB C
• Mice, Inbred ICR
• Sarcoma 180 (immunology, therapy)