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Five-year follow-up of opiate addicts with naltrexone and behavior therapy.

Abstract
A group of 58 heroin addicts were treated with naltrexone and behavior therapy and followed for 5 years. At one-year post-treatment, almost half of the naltrexone-treated subjects were opiate free. Follow-up results at 5 years post-treatment indicate that over 90% of those patients treated with naltrexone became re-addicted for various periods of time. However, naltrexone-treated subjects did feel their treatment with naltrexone had provided them with the ability to remain opiate free for blocks of time. The results suggest that naltrexone is not a "cure" for opiate dependence, but is a medication which can be useful in protecting patients from re-addiction and is a modality patients should be encouraged to return to if they feel vulnerable to re-addiction.
AuthorsR A Rawson, F S Tennant Jr
JournalNIDA research monograph (NIDA Res Monogr) Vol. 49 Pg. 289-95 (Mar 1984) ISSN: 1046-9516 [Print] United States
PMID6434974 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Naloxone
  • Naltrexone
Topics
  • Adult
  • Behavior Therapy (methods)
  • Combined Modality Therapy
  • Follow-Up Studies
  • Heroin Dependence (rehabilitation)
  • Humans
  • Male
  • Naloxone (analogs & derivatives)
  • Naltrexone (therapeutic use)
  • Recurrence

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