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Use of a superactive luteinizing hormone releasing hormone (LHRH) agonist in the treatment of menorrhagia.

Abstract
A luteinizing hormone releasing hormone agonist, D-Ser(But)6des Gly10-LHRH ethylamide, was administered intranasally to four women with unexplained ovulatory menorrhagia. Dramatic reductions in excessive menstrual blood losses were induced without significant side-effects, although the pattern of loss returned to pretreatment levels within 2 months of ceasing therapy.
AuthorsR W Shaw, H M Fraser
JournalBritish journal of obstetrics and gynaecology (Br J Obstet Gynaecol) Vol. 91 Issue 9 Pg. 913-6 (Sep 1984) ISSN: 0306-5456 [Print] ENGLAND
PMID6433966 (Publication Type: Journal Article)
Chemical References
  • Estrogens
  • Hemoglobins
  • Creatinine
  • Buserelin
Topics
  • Adult
  • Buserelin (therapeutic use)
  • Creatinine (urine)
  • Estrogens (urine)
  • Female
  • Hemoglobins (analysis)
  • Humans
  • Menorrhagia (drug therapy, physiopathology, urine)
  • Menstruation
  • Ovulation (drug effects)

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