Abstract |
The effects of thyrotropin-releasing hormone (TRH) and an enzyme-resistant analogue, MK-771, were compared on punished responding of squirrel monkeys maintained either by food presentation or stimulus- shock termination. Both TRH and MK-771 (1.0-30 mg/kg IM) produced dose-related decreases in punished responding maintained by food presentation and dose-related increases in punished responding maintained by shock termination. TRH was more potent than MK-771 in altering punished response rates maintained by either event.
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Authors | L S Brady, J O Valentine, J E Barrett |
Journal | Psychopharmacology
(Psychopharmacology (Berl))
Vol. 83
Issue 2
Pg. 151-4
( 1984)
ISSN: 0033-3158 [Print] Germany |
PMID | 6431464
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Thiazolidines
- Thyrotropin-Releasing Hormone
- pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide
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Topics |
- Animals
- Conditioning, Psychological
(drug effects)
- Food
- Male
- Punishment
- Saimiri
- Thiazolidines
- Thyrotropin-Releasing Hormone
(analogs & derivatives, pharmacology)
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