Stress and epilepsy: the value of a benzodiazepine--lorazepam.

Abstract

Twenty four patients with drug resistant epilepsy were given lorazepam and placebo added to their pre-existing drug regime. With lorazepam there was a significant reduction in seizures, especially in those with focal and partial complex attacks. The drug proved effective whether or not the patients regarded stress as a trigger to their seizures, but on the Middlesex Hospital Questionnaire there were differences between those with high and low scores.

• Authors: A Moffett, D F Scott
• Journal: Journal of neurology, neurosurgery, and psychiatry (J Neurol Neurosurg Psychiatry) Vol. 47 Issue 2 Pg. 165-7 (Feb 1984) ISSN: 0022-3050 [Print] England
• PMID: 6423775 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anticonvulsants
• Lorazepam

Topics

• Adult
• Anticonvulsants (therapeutic use)
• Drug Therapy, Combination
• Electroencephalography
• Epilepsies, Partial (drug therapy)
• Epilepsy, Temporal Lobe (drug therapy)
• Evoked Potentials (drug effects)
• Female
• Humans
• Lorazepam (therapeutic use)
• Male
• Middle Aged
• Stress, Psychological (complications, drug therapy)