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Combination therapy for dendritic keratitis. High-titer alpha-interferon and trifluridine.

Abstract
Previous studies showed that the combination of trifluridine with human leukocyte interferon in the treatment of dendritic keratitis is effective, and that the best results were obtained with the highest titer then available (30 X 10(6) IU/mL). The present study was undertaken to see if an even higher titer (100 X 10(6) IU/mL) would be more effective. A statistically significant greater effectiveness of the higher titer could not be verified.
AuthorsR Sundmacher, K Cantell, A Mattes
JournalArchives of ophthalmology (Chicago, Ill. : 1960) (Arch Ophthalmol) Vol. 102 Issue 4 Pg. 554-5 (Apr 1984) ISSN: 0003-9950 [Print] United States
PMID6422914 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Interferon Type I
  • Trifluridine
  • Thymidine
Topics
  • Drug Therapy, Combination
  • Humans
  • Interferon Type I (administration & dosage)
  • Keratitis, Dendritic (drug therapy)
  • Thymidine (analogs & derivatives)
  • Trifluridine (administration & dosage)

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