Abstract |
The 3' terminal region from the LEU2 gene of yeast has been sequenced. Two open reading frames (ORF) have been identified, one of which constitutes the 3' terminus of beta-isopropylmalate dehydrogenase, the product of the LEU2 gene. A noncoding spacer region located between the ORFs contains two consensus-type transcriptional terminators. The terminator-like sequences are oriented in opposing directions on opposite DNA strands. The noncoding spacer region may represent a single terminator for the LEU2 gene or two separate terminators involved in blocking convergent transcription from an as yet unidentified yeast gene.
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Authors | B E Froman, R C Tait, R L Rodriguez |
Journal | Gene
(Gene)
Vol. 31
Issue 1-3
Pg. 257-61
(Nov 1984)
ISSN: 0378-1119 [Print] Netherlands |
PMID | 6396161
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Fungal Proteins
- Alcohol Oxidoreductases
- 3-Isopropylmalate Dehydrogenase
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Topics |
- 3-Isopropylmalate Dehydrogenase
- Alcohol Oxidoreductases
(genetics)
- Amino Acid Sequence
- Base Sequence
- Fungal Proteins
(genetics)
- Genes
- Genes, Fungal
- Saccharomyces cerevisiae
(enzymology, genetics)
- Transcription, Genetic
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