Late meningeal effects of myelographic contrast media with special reference to metrizamide.

Abstract

Two hundred and fifty-six myelograms in 192 patients were following by repeat myelography using a water-soluble contrast medium. The films of these re-examinations were analysed for signs of meningeal changes. Adhesive arachnoiditis had developed in five of 46 cases after methiodal sodium, in 24 of 96 cases after iothalamate meglumine, in seven of 12 cases after iocarmate meglumine, in seven of ten cases after iodophendylate, but in none of 90 cases after metrizamide. Dose of contrast medium, observation time and protein concentration of the CSF were found to be factors of importance for the development of adhesive arachnoiditis.

• Authors: E B Hansen, A Fahrenkrug, J Praestholm
• Journal: The British journal of radiology (Br J Radiol) Vol. 51 Issue 605 Pg. 321-7 (May 1978) ISSN: 0007-1285 [Print] England
• PMID: 638401 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Cerebrospinal Fluid Proteins
• Contrast Media
• Metrizamide

Topics

• Adolescent
• Adult
• Arachnoiditis (chemically induced)
• Cerebrospinal Fluid Proteins (analysis)
• Contrast Media (administration & dosage, adverse effects)
• Female
• Humans
• Lumbosacral Region (diagnostic imaging)
• Male
• Meninges (drug effects)
• Metrizamide (adverse effects)
• Middle Aged
• Myelography (adverse effects)
• Surgical Procedures, Operative (adverse effects)
• Time Factors