[Effect of anabolic steroid on immune response].

Abstract

Using lymphocyte, monocyte and eosinophil counts of the peripheral blood, PHA-blastoid transformation, immunoglobulin and beta 2-microglobulin, the influence of anabolic steroid on the immune reactivity of the host was dissected by administration of Deca-Durabolin ( nandrolone decanoate) to both tumor-bearing host and tumor-free host after operation for alimentary tract. The number of peripheral lymphocytes and monocytes, the PHA-blastoid transformation of peripheral lymphocytes and the IgG level were increased, and the beta 2-microglobulin level showed the tendency of decrease after the administration of Deca-Durabolin.

• Authors: H Yamagishi, M Kobayashi, H Konosu, H Kurioka, K Naito, T Sonoyama, T Nishimoto, I Hashimoto
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 11 Issue 3 Pg. 420-6 (Mar 1984) ISSN: 0385-0684 [Print] Japan
• PMID: 6367663 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulin A
• Immunoglobulin G
• Immunoglobulin M
• beta 2-Microglobulin
• Nandrolone
• Nandrolone Decanoate

Topics

• Female
• Gastrointestinal Neoplasms (immunology)
• Humans
• Immunity, Cellular
• Immunoglobulin A (analysis)
• Immunoglobulin G (analysis)
• Immunoglobulin M (analysis)
• Leukocyte Count
• Lymphocyte Activation (drug effects)
• Lymphocytes (drug effects, immunology)
• Middle Aged
• Monocytes (immunology)
• Nandrolone (administration & dosage, analogs & derivatives, pharmacology)
• Nandrolone Decanoate
• Neoplasms (immunology)
• beta 2-Microglobulin (analysis)