Calcium antagonists in hypertensive disease: experimental evidence for a new therapeutic concept.

Abstract	In animal experiments calcium antagonist drugs decrease peripheral vascular resistance, improve renal sodium excretion and thus, diminishing the volume load, reduce cardiac hypertrophy. In experimental malignant hypertension these drugs preserve tissue integrity by inhibiting the deleterious calcium overload of vessels.
Authors	S Kazda, B Garthoff, G Luckhaus
Journal	Postgraduate medical journal (Postgrad Med J) Vol. 59 Suppl 2 Pg. 78-83 ( 1983) ISSN: 0032-5473 [Print] England
PMID	6351044 (Publication Type: Journal Article, Review)
Chemical References	Calcium Channel Blockers Calcium
Topics	Animals Arteries (metabolism) Blood Pressure (drug effects) Calcium (metabolism) Calcium Channel Blockers (therapeutic use) Hypertension (complications, drug therapy, pathology) Hypertension, Malignant (drug therapy) Male Rats Vascular Diseases (drug therapy, etiology)

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