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Unusual manifestations of secondary syphilis occurring after orthotopic liver transplantation.

Abstract
A 48-year-old actively homosexual man who had undergone liver transplantation for cirrhosis secondary to hepatitis B infection six years previously presented with a syndrome of diffuse pain, cholestasis, and low-grade fever. The development of thrombocytopenia and persistent hypoprothrombinemia precluded liver biopsy. Subsequently, a skin eruption and VDRL result of 1:128 indicated that most of the findings could be explained by a diagnosis of secondary syphilis with luetic hepatitis and periostitis. This impression was confirmed by a complete response to penicillin therapy. The relation of thrombocytopenia to lues in this case remains uncertain.
AuthorsL R Petersen, R H Mead, M G Perlroth
JournalThe American journal of medicine (Am J Med) Vol. 75 Issue 1 Pg. 166-70 (Jul 1983) ISSN: 0002-9343 [Print] United States
PMID6344633 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Penicillins
Topics
  • Hepatitis (drug therapy, etiology)
  • Humans
  • Hypoprothrombinemias (etiology)
  • Liver Transplantation
  • Male
  • Middle Aged
  • Penicillins (therapeutic use)
  • Periostitis (etiology)
  • Postoperative Complications
  • Syphilis (drug therapy, etiology)
  • Thrombocytopenia (etiology)

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